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The Mitochondrial Na(+)/Ca(2+) Exchanger Inhibitor CGP37157 Preserves Muscle Structure and Function to Increase Lifespan and Healthspan in Caenorhabditis elegans
We have reported recently that the mitochondrial Na(+)/Ca(2+) exchanger inhibitor CGP37157 extends lifespan in Caenorhabditis elegans by a mechanism involving mitochondria, the TOR pathway and the insulin/IGF1 pathway. Here we show that CGP37157 significantly improved the evolution with age of the s...
Shranjeno v:
| izdano v: | Front Pharmacol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8241105/ https://ncbi.nlm.nih.gov/pubmed/34211399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.695687 |
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