Electrosteric stealth Rivastigmine loaded liposomes for brain targeting: preparation, characterization, ex vivo, bio-distribution and in vivo pharmacokinetic studies

Being one of the highly effective drugs in treatment of Alzheimer’s disease, Rivastigmine brain targeting is highly demandable, therefore liposomal dispersion of Rivastigmine was prepared containing 2 mol% PEG-DSPE added to Lecithin, Didecyldimethyl ammonium bromide (DDAB), Tween 80 in 1:0.02:0.25 m...

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Detalles Bibliográficos
Publicado en:Drug Deliv
Main Authors: Nageeb El-Helaly, Sara, Abd Elbary, Ahmed, Kassem, Mohamed A., El-Nabarawi, Mohamed A.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240971/
https://ncbi.nlm.nih.gov/pubmed/28415883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2017.1309476
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