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Electrosteric stealth Rivastigmine loaded liposomes for brain targeting: preparation, characterization, ex vivo, bio-distribution and in vivo pharmacokinetic studies

Being one of the highly effective drugs in treatment of Alzheimer’s disease, Rivastigmine brain targeting is highly demandable, therefore liposomal dispersion of Rivastigmine was prepared containing 2 mol% PEG-DSPE added to Lecithin, Didecyldimethyl ammonium bromide (DDAB), Tween 80 in 1:0.02:0.25 m...

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Dettagli Bibliografici
Pubblicato in:Drug Deliv
Autori principali: Nageeb El-Helaly, Sara, Abd Elbary, Ahmed, Kassem, Mohamed A., El-Nabarawi, Mohamed A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240971/
https://ncbi.nlm.nih.gov/pubmed/28415883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2017.1309476
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