Enhanced Transdermal Delivery of Bisoprolol Hemifumarate via Combined Effect of Iontophoresis and Chemical Enhancers: Ex Vivo Permeation/In Vivo Pharmacokinetic Studies

Bisoprolol hemifumarate (BH) is an antihypertensive drug that is used as first-line treatment for chronic hypertension and angina pectoris. Our study was performed to enhance the transdermal delivery of BH, a hydrophilic drug active with high molecular weight, through differently prepared hydrogels....

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Vydáno v:Pharmaceutics
Hlavní autoři: Teaima, Mahmoud H., Mohamed, Mohamed Azmi Ahmed, Abd El Rehem, Randa Tag, Tayel, Saadia A., El-Nabarawi, Mohamed A., Fouad, Shahinaze A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151755/
https://ncbi.nlm.nih.gov/pubmed/34068544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13050682
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