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mRNA Delivery of a Bispecific Single Domain Antibody to Polarize Tumor-associated Macrophages and Synergize Immunotherapy Against Liver Malignancies
Liver malignancies are among the tumor types that are resistant to immune checkpoint inhibition therapy. Tumor-associated macrophages (TAMs) are highly enriched and play a major role in inducing immunosuppression in liver malignancies. Herein, CCL2 and CCL5 are screened as two major chemokines respo...
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| Publicado no: | Adv Mater |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8240965/ https://ncbi.nlm.nih.gov/pubmed/33945178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.202007603 |
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