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Cancer immunotherapy with T cells carrying bispecific receptors that mimic antibodies

Tumors are inherently heterogeneous in antigen expression and escape from immune surveillance due to antigen loss remains one of the limitations of targeted immunotherapy. Despite the clinical use of adoptive therapy with chimeric antigen receptor (CAR)–redirected T cells in lymphoblastic leukemia,...

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Podrobná bibliografie
Vydáno v:Cancer Immunol Res
Hlavní autoři: Ahn, Sarah, Li, Jingjing, Sun, Chuang, Gao, Keliang, Hirabayashi, Koichi, Li, Hongxia, Savoldo, Barbara, Liu, Rihe, Dotti, Gianpietro
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760241/
https://ncbi.nlm.nih.gov/pubmed/30842091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0636
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