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Cancer immunotherapy with T cells carrying bispecific receptors that mimic antibodies

Tumors are inherently heterogeneous in antigen expression and escape from immune surveillance due to antigen loss remains one of the limitations of targeted immunotherapy. Despite the clinical use of adoptive therapy with chimeric antigen receptor (CAR)–redirected T cells in lymphoblastic leukemia,...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Ahn, Sarah, Li, Jingjing, Sun, Chuang, Gao, Keliang, Hirabayashi, Koichi, Li, Hongxia, Savoldo, Barbara, Liu, Rihe, Dotti, Gianpietro
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760241/
https://ncbi.nlm.nih.gov/pubmed/30842091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0636
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