Overexpression of lipoic acid synthase gene alleviates diabetic nephropathy of Lepr(db/db) mice

INTRODUCTION: Diabetic nephropathy (DN) develops in about 40% of patients with type 2 diabetes and remains the leading cause of end-stage renal disease. The mechanisms of DN remain to be elucidated. Oxidative stress is thought to be involved in the development of DN but antioxidant therapy has produ...

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Bibliografiset tiedot
Julkaisussa:BMJ Open Diabetes Res Care
Päätekijät: Zhao, Yingzheng, Yan, Tingting, Xiong, Cheng, Chang, Meiyu, Gao, Qiyu, Yao, Sanqiao, Wu, Weidong, Yi, Xianwen, Xu, Guangcui
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMJ Publishing Group 2021
Aiheet:
Metabolism
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240563/
https://ncbi.nlm.nih.gov/pubmed/34183321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2021-002260
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