DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy

BACKGROUND: Sex is an important covariate of epigenome-wide association studies due to its strong influence on DNA methylation patterns across numerous genomic positions. Nevertheless, many samples on the Gene Expression Omnibus (GEO) frequently lack a sex annotation or are incorrectly labelled. Con...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Wang, Yucheng, Hannon, Eilis, Grant, Olivia A., Gorrie-Stone, Tyler J., Kumari, Meena, Mill, Jonathan, Zhai, Xiaojun, McDonald-Maier, Klaus D., Schalkwyk, Leonard C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240370/
https://ncbi.nlm.nih.gov/pubmed/34182928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-021-07675-2
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