Leveraging DNA-Methylation Quantitative-Trait Loci to Characterize the Relationship between Methylomic Variation, Gene Expression, and Complex Traits

Characterizing the complex relationship between genetic, epigenetic, and transcriptomic variation has the potential to increase understanding about the mechanisms underpinning health and disease phenotypes. We undertook a comprehensive analysis of common genetic variation on DNA methylation (DNAm) b...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Hannon, Eilis, Gorrie-Stone, Tyler J., Smart, Melissa C., Burrage, Joe, Hughes, Amanda, Bao, Yanchun, Kumari, Meena, Schalkwyk, Leonard C., Mill, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217758/
https://ncbi.nlm.nih.gov/pubmed/30401456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2018.09.007
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