Efficacy of YAP1-gene Knockdown to Inhibit Alveolar-Epithelial-Cell Senescence and Alleviate Idiopathic Pulmonary Fibrosis (IPF)

Background/Aim: The prevalence of idiopathic pulmonary fibrosis (IPF) increases with age and is associated with senescence of alveolar epithelial cells (AECs). AEC senescence in pulmonary cells mediates IPF. We herein aimed to determine if YAP1 gene knockdown, a member of the Hippo/YAP signal pathwa...

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Detalhes bibliográficos
Publicado no:Cancer Genomics Proteomics
Main Authors: XU, WEI, SONG, WEIWEI, WANG, YU, ZAN, YUMIN, ZHANG, MINGJIONG, LI, MIN, HUANG, QIQING, ZHAO, WEIHONG, SUN, YU, HOFFMAN, ROBERT M, WU, JIANQING
Formato: Artigo
Idioma:Inglês
Publicado em: International Institute of Anticancer Research 2021
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240039/
https://ncbi.nlm.nih.gov/pubmed/33994367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20271
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