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Efficacy of YAP1-gene Knockdown to Inhibit Alveolar-Epithelial-Cell Senescence and Alleviate Idiopathic Pulmonary Fibrosis (IPF)

Background/Aim: The prevalence of idiopathic pulmonary fibrosis (IPF) increases with age and is associated with senescence of alveolar epithelial cells (AECs). AEC senescence in pulmonary cells mediates IPF. We herein aimed to determine if YAP1 gene knockdown, a member of the Hippo/YAP signal pathwa...

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Dettagli Bibliografici
Pubblicato in:Cancer Genomics Proteomics
Autori principali: XU, WEI, SONG, WEIWEI, WANG, YU, ZAN, YUMIN, ZHANG, MINGJIONG, LI, MIN, HUANG, QIQING, ZHAO, WEIHONG, SUN, YU, HOFFMAN, ROBERT M, WU, JIANQING
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Institute of Anticancer Research 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240039/
https://ncbi.nlm.nih.gov/pubmed/33994367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20271
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