MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway

Background: Acute myeloid leukemia (AML) is a group of heterogeneous hematologic malignancies correlates with poor prognosis. It is important to identify biomarkers for effective treatment of AML. Kinases participate in many regulatory pathways and biological activities in AML. Previous studies demo...

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Библиографические подробности
Опубликовано в: :EBioMedicine
Главные авторы: Ling, Qing, Li, Fenglin, Zhang, Xiang, Mao, Shihui, Lin, Xiangjie, Pan, Jiajia, Ye, Wenle, Wei, Wenwen, Qian, Yu, Hu, Chao, Huang, Xin, Wang, Jinghan, Wang, Huafeng, Huang, Jiansong, Wang, Yungui, Jin, Jie
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2021
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239467/
https://ncbi.nlm.nih.gov/pubmed/34166980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103441
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