MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway

Background: Acute myeloid leukemia (AML) is a group of heterogeneous hematologic malignancies correlates with poor prognosis. It is important to identify biomarkers for effective treatment of AML. Kinases participate in many regulatory pathways and biological activities in AML. Previous studies demo...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Ling, Qing, Li, Fenglin, Zhang, Xiang, Mao, Shihui, Lin, Xiangjie, Pan, Jiajia, Ye, Wenle, Wei, Wenwen, Qian, Yu, Hu, Chao, Huang, Xin, Wang, Jinghan, Wang, Huafeng, Huang, Jiansong, Wang, Yungui, Jin, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239467/
https://ncbi.nlm.nih.gov/pubmed/34166980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103441
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