High content genome-wide siRNA screen to investigate the coordination of cell size and RNA production

Coordination of RNA abundance and production rate with cell size has been observed in diverse organisms and cell populations. However, how cells achieve such ‘scaling’ of transcription with size is unknown. Here we describe a genome-wide siRNA screen to identify regulators of global RNA production r...

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Veröffentlicht in:Sci Data
Hauptverfasser: Müller, Micha, Avar, Merve, Heinzer, Daniel, Emmenegger, Marc, Aguzzi, Adriano, Pelkmans, Lucas, Berry, Scott
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Data Descriptor
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239010/
https://ncbi.nlm.nih.gov/pubmed/34183683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41597-021-00944-5
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