RNA Fibers as Optimized Nanoscaffolds for siRNA Coordination and Reduced Immunological Recognition

RNA is a versatile biomaterial that can be used to engineer nanoassemblies for personalized treatment of various diseases. Despite promising advancements, the design of RNA nanoassemblies with minimal recognition by the immune system remains a major challenge. Here, an approach is reported to engine...

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Vydáno v:Adv Funct Mater
Hlavní autoři: Rackley, Lauren, Stewart, Jaimie Marie, Salotti, Jacqueline, Krokhotin, Andrey, Shah, Ankit, Halman, Justin R., Juneja, Ridhima, Smollett, Jaclyn, Lee, Lauren, Roark, Kyle, Viard, Mathias, Tarannum, Mubin, Vivero-Escoto, Juan, Johnson, Peter F., Dobrovolskaia, Marina A., Dokholyan, Nikolay V., Franco, Elisa, Afonin, Kirill A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599627/
https://ncbi.nlm.nih.gov/pubmed/31258458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adfm.201805959
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