High content genome-wide siRNA screen to investigate the coordination of cell size and RNA production

Coordination of RNA abundance and production rate with cell size has been observed in diverse organisms and cell populations. However, how cells achieve such ‘scaling’ of transcription with size is unknown. Here we describe a genome-wide siRNA screen to identify regulators of global RNA production r...

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Bibliografische gegevens
Gepubliceerd in:Sci Data
Hoofdauteurs: Müller, Micha, Avar, Merve, Heinzer, Daniel, Emmenegger, Marc, Aguzzi, Adriano, Pelkmans, Lucas, Berry, Scott
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239010/
https://ncbi.nlm.nih.gov/pubmed/34183683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41597-021-00944-5
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