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Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells

Background: Resistance to antiproliferative chemotherapies remains a significant challenge in the care of patients with solid tumors. Glucocorticoids, including endogenous cortisol, have been shown to induce pro-survival pathways in epithelial tumor cells. While pro-apoptotic effects of glucocortico...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Greenstein, Andrew E., Hunt, Hazel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238250/
https://ncbi.nlm.nih.gov/pubmed/34194622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27989
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