Antagonism of Tumoral Prolactin Receptor Promotes Autophagy Related Cell Death

Summary Therapeutic upregulation of macroautophagy in cancer cells provides an alternative mechanism for cell death. Prolactin (PRL) and its receptor (PRLR) are considered attractive therapeutic targets because of their roles as growth factors in tumor growth and progression. We utilized a novel ant...

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Detaylı Bibliyografya
Asıl Yazarlar: Wen, Yunfei, Zand, Behrouz, Ozpolat, Bulent, Szczepanski, Miroslaw J., Lu, Chunhua, Yuca, Erkan, Carroll, Amy R., Alpay, Neslihan, Bartholomeusz, Chandra, Tekedereli, Ibrahim, Kang, Yu, Rupaimoole, Rajesha, Pecot, Chad V., Dalton, Heather J., Hernandez, Anadulce, Lokshin, Anna, Lutgendorf, Susan K., Liu, Jinsong, Hittelman, Walter N., Chen, Wen Y., Lopez-Berestein, Gabriel, Szajnik, Marta, Ueno, Naoto T., Coleman, Robert L., Sood, Anil K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038960/
https://ncbi.nlm.nih.gov/pubmed/24703838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.009
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