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Drug distribution along the cochlea is strongly enhanced by low-frequency round window micro vibrations

The cochlea’s inaccessibility and complex nature provide significant challenges to delivering drugs and other agents uniformly, safely and efficiently, along the entire cochlear spiral. Large drug concentration gradients are formed along the cochlea when drugs are administered to the middle ear. Thi...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Flaherty, Samuel M., Russell, Ian J., Lukashkin, Andrei N.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238068/
https://ncbi.nlm.nih.gov/pubmed/34176371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2021.1943059
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