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Drug Diffusion Along an Intact Mammalian Cochlea

Intratympanic drug administration depends on the ability of drugs to pass through the round window membrane (RW) at the base of the cochlea and diffuse from this location to the apex. While the RW permeability for many different drugs can be promoted, passive diffusion along the narrowing spiral of...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Sadreev, Ildar I., Burwood, George W. S., Flaherty, Samuel M., Kim, Jongrae, Russell, Ian J., Abdullin, Timur I., Lukashkin, Andrei N.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497751/
https://ncbi.nlm.nih.gov/pubmed/31080407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00161
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