Drug Diffusion Along an Intact Mammalian Cochlea

Intratympanic drug administration depends on the ability of drugs to pass through the round window membrane (RW) at the base of the cochlea and diffuse from this location to the apex. While the RW permeability for many different drugs can be promoted, passive diffusion along the narrowing spiral of...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Sadreev, Ildar I., Burwood, George W. S., Flaherty, Samuel M., Kim, Jongrae, Russell, Ian J., Abdullin, Timur I., Lukashkin, Andrei N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Cellular Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497751/
https://ncbi.nlm.nih.gov/pubmed/31080407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00161
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