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Host immunity following near-infrared photoimmunotherapy is enhanced with PD-1 checkpoint blockade to eradicate established antigenic tumors

Near-infrared photoimmunotherapy (NIR-PIT) induces immunogenic cell death, but has mostly failed to induce durable antitumor responses in syngenic tumor mouse models. We hypothesized that adaptive immune resistance could be limiting durable responses after treatmemt with NIR-PIT. We investigated the...

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Vydáno v:Cancer Immunol Res
Hlavní autoři: Nagaya, Tadanobu, Friedman, Jay, Maruoka, Yasuhiro, Ogata, Fusa, Okuyama, Shuhei, Clavijo, Paul E., Choyke, Peter L., Allen, Clint, Kobayashi, Hisataka
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237708/
https://ncbi.nlm.nih.gov/pubmed/30683733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0546
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