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Host immunity following near-infrared photoimmunotherapy is enhanced with PD-1 checkpoint blockade to eradicate established antigenic tumors

Near-infrared photoimmunotherapy (NIR-PIT) induces immunogenic cell death, but has mostly failed to induce durable antitumor responses in syngenic tumor mouse models. We hypothesized that adaptive immune resistance could be limiting durable responses after treatmemt with NIR-PIT. We investigated the...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Nagaya, Tadanobu, Friedman, Jay, Maruoka, Yasuhiro, Ogata, Fusa, Okuyama, Shuhei, Clavijo, Paul E., Choyke, Peter L., Allen, Clint, Kobayashi, Hisataka
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237708/
https://ncbi.nlm.nih.gov/pubmed/30683733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0546
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