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Host immunity following near-infrared photoimmunotherapy is enhanced with PD-1 checkpoint blockade to eradicate established antigenic tumors

Near-infrared photoimmunotherapy (NIR-PIT) induces immunogenic cell death, but has mostly failed to induce durable antitumor responses in syngenic tumor mouse models. We hypothesized that adaptive immune resistance could be limiting durable responses after treatmemt with NIR-PIT. We investigated the...

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Bibliografiske detaljer
Udgivet i:Cancer Immunol Res
Main Authors: Nagaya, Tadanobu, Friedman, Jay, Maruoka, Yasuhiro, Ogata, Fusa, Okuyama, Shuhei, Clavijo, Paul E., Choyke, Peter L., Allen, Clint, Kobayashi, Hisataka
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237708/
https://ncbi.nlm.nih.gov/pubmed/30683733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0546
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