A novel imidazolinone metformin‐methylglyoxal metabolite promotes endothelial cell angiogenesis via the eNOS/HIF‐1α pathway

Peripheral arterial disease (PAD) is one of the major complications of diabetes due to an impairment in angiogenesis. Since there is currently no drug with satisfactory efficacy to enhance blood vessel formation, discovering therapies to improve angiogenesis is critical. An imidazolinone metabolite...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Nguyen, Huong, Koh, Jia Yi, Li, Hainan, Islas‐Robles, Argel, Meda Venkata, Sai Pranathi, Wang, Jie‐Mei, Monks, Terrence J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237315/
https://ncbi.nlm.nih.gov/pubmed/34105824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202002674RR
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