Ameliorating Methylglyoxal-Induced Progenitor Cell Dysfunction for Tissue Repair in Diabetes

Patient-derived progenitor cell (PC) dysfunction is severely impaired in diabetes, but the molecular triggers that contribute to mechanisms of PC dysfunction are not fully understood. Methylglyoxal (MGO) is one of the highly reactive dicarbonyl species formed during hyperglycemia. We hypothesized th...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Li, Hainan, O’Meara, Megan, Zhang, Xiang, Zhang, Kezhong, Seyoum, Berhane, Yi, Zhengping, Kaufman, Randal J., Monks, Terrence J., Wang, Jie-Mei
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2019
Assuntos:
Complications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610016/
https://ncbi.nlm.nih.gov/pubmed/30885990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0933
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