Ameliorating Methylglyoxal-Induced Progenitor Cell Dysfunction for Tissue Repair in Diabetes

Patient-derived progenitor cell (PC) dysfunction is severely impaired in diabetes, but the molecular triggers that contribute to mechanisms of PC dysfunction are not fully understood. Methylglyoxal (MGO) is one of the highly reactive dicarbonyl species formed during hyperglycemia. We hypothesized th...

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Vydáno v:Diabetes
Hlavní autoři: Li, Hainan, O’Meara, Megan, Zhang, Xiang, Zhang, Kezhong, Seyoum, Berhane, Yi, Zhengping, Kaufman, Randal J., Monks, Terrence J., Wang, Jie-Mei
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2019
Témata:
Complications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610016/
https://ncbi.nlm.nih.gov/pubmed/30885990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0933
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