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Improving the Gastrointestinal Stability of Linaclotide
[Image: see text] High susceptibility to proteolytic degradation in the gastrointestinal tract limits the therapeutic application of peptide drugs in gastrointestinal disorders. Linaclotide is an orally administered peptide drug for the treatment of irritable bowel syndrome with constipation (IBS-C)...
Salvato in:
| Pubblicato in: | J Med Chem |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2021
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8237258/ https://ncbi.nlm.nih.gov/pubmed/33979161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.1c00380 |
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