Daunorubicin-containing CLL1-targeting nanomicelles have anti-leukemia stem cell activity in acute myeloid leukemia

Patients with acute myeloid leukemia have a very poor prognosis related to a high rate of relapse and drug-related toxicity. The ability of leukemia stem cells (LSCs) to survive chemotherapy is primarily responsible for relapse, and eliminating LSCs is ultimately essential for cure. We developed nov...

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Pubblicato in:Nanomedicine
Autori principali: Lin, Tzu-yin, Zhu, Yanjun, Li, Yuanpei, Zhang, Hongyong, Ma, Ai-Hong, Long, Qilai, Keck, James, Lam, Kit S., Pan, Chong-xian, Jonas, Brian A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237247/
https://ncbi.nlm.nih.gov/pubmed/31055076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2019.04.007
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