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Characterization of high-affinity peptides and their feasibility for use in nanotherapeutics targeting leukemia stem cells

Peptides featuring the LR(S/T) motif were identified that could specifically target CLL1. Nanomicelles conjugated to CCL1-targeting peptides were loaded with DiI or daunorubicin during synthesis. The resulting nanomicelles were approximately 15 nm in diameter, had high affinity for cells expressing...

詳細記述

保存先:
書誌詳細
出版年:Nanomedicine
主要な著者: Zhang, Hongyong, Luo, Juntao, Li, Yuanpei, Henderson, Paul T, Wachsmann-Hogiu, Sebastian, Lam, Kit S., Pan, Chong-xian
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577023/
https://ncbi.nlm.nih.gov/pubmed/22197725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2011.12.004
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