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Characterization of high-affinity peptides and their feasibility for use in nanotherapeutics targeting leukemia stem cells
Peptides featuring the LR(S/T) motif were identified that could specifically target CLL1. Nanomicelles conjugated to CCL1-targeting peptides were loaded with DiI or daunorubicin during synthesis. The resulting nanomicelles were approximately 15 nm in diameter, had high affinity for cells expressing...
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| Publicado no: | Nanomedicine |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4577023/ https://ncbi.nlm.nih.gov/pubmed/22197725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2011.12.004 |
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