Population pharmacokinetics of Daunorubicin in adult patients with acute myeloid leukemia

PURPOSE: Chemotherapy drug resistance and relapse of the disease have been the major factors limiting the success of acute myeloid leukemia (AML) therapy. Several factors, including the pharmacokinetics (PK) of Cytarabine (Ara-C) and Daunorubicin (Dnr), could contribute to difference in treatment ou...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Varatharajan, Savitha, Panetta, John C., Abraham, Ajay, Karathedath, Sreeja, Mohanan, Ezhilpavai, Lakshmi, Kavitha M., Arthur, Nancy, Srivastava, Vivi M., Nemani, Sandeep, George, Biju, Srivastava, Alok, Mathews, Vikram, Balasubramanian, Poonkuzhali
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115946/
https://ncbi.nlm.nih.gov/pubmed/27738808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-016-3166-8
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