RNA expression of genes involved in cytarabine metabolism and transport predicts cytarabine response in acute myeloid leukemia

BACKGROUND: Variation in terms of outcome and toxic side effects of treatment exists among acute myeloid leukemia (AML) patients on chemotherapy with cytarabine (Ara-C) and daunorubicin (Dnr). Candidate Ara-C metabolizing gene expression in primary AML cells is proposed to account for this variation...

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Publicado no:Pharmacogenomics
Main Authors: Abraham, Ajay, Varatharajan, Savitha, Karathedath, Sreeja, Philip, Chepsy, Lakshmi, Kavitha M, Jayavelu, Ashok Kumar, Mohanan, Ezhilpavai, Janet, Nancy Beryl, Srivastava, Vivi M, Shaji, Ramachandran V, Zhang, Wei, Abraham, Aby, Viswabandya, Auro, George, Biju, Chandy, Mammen, Srivastava, Alok, Mathews, Vikram, Balasubramanian, Poonkuzhali
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115907/
https://ncbi.nlm.nih.gov/pubmed/26083014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.15.44
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