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Skeletal muscle‐specific over‐expression of the nuclear sirtuin SIRT6 blocks cancer‐associated cachexia by regulating multiple targets

BACKGROUND: During cancer cachexia, cytokines released from tumour cells can alter body's metabolism, which can lead to onset of this disease process. Biological basis of cachexia is multifactorial; hence, it is important to identify and modulate multiple targets to curtail the process of cache...

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Bibliografske podrobnosti
izdano v:JCSM Rapid Commun
Main Authors: Samant, Sadhana A., Pillai, Vinodkumar B., Gupta, Mahesh P.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237231/
https://ncbi.nlm.nih.gov/pubmed/34212132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rco2.27
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