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The nuclear and mitochondrial sirtuins, Sirt6 and Sirt3, regulate each other’s activity and protect the heart from developing obesity-mediated diabetic cardiomyopathy
Sirtuins (Sirts) are implicated in regulating a myriad of biologic functions ranging from cell growth and metabolism to longevity. Here, we show that nuclear Sirt, Sirt6, and mitochondrial Sirt, Sirt3, regulate each other’s activity and protect the heart from developing diabetic cardiomyopathy. We f...
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| Wydane w: | FASEB J |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Federation of American Societies for Experimental Biology
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6766651/ https://ncbi.nlm.nih.gov/pubmed/31318577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900767R |
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