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The nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy

Sirtuins have been shown to regulate the aging process. We have previously demonstrated that Sirt6 blocks the pressure overload-induced cardiac hypertrophy in mice. Here, we show that Sirt6 can also mitigate aging-induced cardiomyocyte senescence and cardiac hypertrophy. We found that aging is assoc...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Aging (Albany NY)
Päätekijät: Pillai, Vinodkumar B., Samant, Sadhana, Hund, Samantha, Gupta, Madhu, Gupta, Mahesh P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8148452/
https://ncbi.nlm.nih.gov/pubmed/33934090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.203027
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