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The nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy

Sirtuins have been shown to regulate the aging process. We have previously demonstrated that Sirt6 blocks the pressure overload-induced cardiac hypertrophy in mice. Here, we show that Sirt6 can also mitigate aging-induced cardiomyocyte senescence and cardiac hypertrophy. We found that aging is assoc...

詳細記述

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書誌詳細
出版年:Aging (Albany NY)
主要な著者: Pillai, Vinodkumar B., Samant, Sadhana, Hund, Samantha, Gupta, Madhu, Gupta, Mahesh P.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8148452/
https://ncbi.nlm.nih.gov/pubmed/33934090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.203027
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