NADH Fluorescence Lifetime Imaging Microscopy Reveals Selective Mitochondrial Dysfunction in Neurons Overexpressing Alzheimer’s Disease–Related Proteins

Alzheimer’s disease (AD), the most prevalent form of dementia, affects globally more than 30 million people suffering from cognitive deficits and neuropsychiatric symptoms. Substantial evidence for the involvement of mitochondrial dysfunction in the development and/or progression of AD has been show...

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Dettagli Bibliografici
Pubblicato in:Front Mol Biosci
Autori principali: Niederschweiberer, Moritz A., Schaefer, Patrick M., Singh, Larry N., Lausser, Ludwig, Bhosale, Devyani, Hesse, Raphael, Calzia, Enrico, Kestler, Hans A., Rueck, Angelika, Wallace, Douglas C., von Einem, Bjoern, von Arnim, Christine A. F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Molecular Biosciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8236706/
https://ncbi.nlm.nih.gov/pubmed/34195227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.671274
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