NADH Fluorescence Lifetime Imaging Microscopy Reveals Selective Mitochondrial Dysfunction in Neurons Overexpressing Alzheimer’s Disease–Related Proteins

Alzheimer’s disease (AD), the most prevalent form of dementia, affects globally more than 30 million people suffering from cognitive deficits and neuropsychiatric symptoms. Substantial evidence for the involvement of mitochondrial dysfunction in the development and/or progression of AD has been show...

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Bibliografische gegevens
Gepubliceerd in:Front Mol Biosci
Hoofdauteurs: Niederschweiberer, Moritz A., Schaefer, Patrick M., Singh, Larry N., Lausser, Ludwig, Bhosale, Devyani, Hesse, Raphael, Calzia, Enrico, Kestler, Hans A., Rueck, Angelika, Wallace, Douglas C., von Einem, Bjoern, von Arnim, Christine A. F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Molecular Biosciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8236706/
https://ncbi.nlm.nih.gov/pubmed/34195227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.671274
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