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WASp Is Crucial for the Unique Architecture of the Immunological Synapse in Germinal Center B-Cells
B-cells undergo somatic hypermutation and affinity maturation in germinal centers. Somatic hypermutated germinal center B-cells (GCBs) compete to engage with and capture antigens on follicular dendritic cells. Recent studies show that when encountering membrane antigens, GCBs generate actin-rich pod...
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| Publicado en: | Front Cell Dev Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8236648/ https://ncbi.nlm.nih.gov/pubmed/34195186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.646077 |
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