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Activation of the Anti-Oxidative Stress Response Reactivates Latent HIV-1 Through the Mitochondrial Antiviral Signaling Protein Isoform MiniMAVS

The mitochondrial antiviral signaling protein (MAVS) is part of the cell’s innate immune mechanism of defense. MAVS mRNA is bicistronic and can give rise to a full length-MAVS and a shorter isoform termed miniMAVS. In response to viral infections, viral RNA can be sensed by the cytosolic RNA sensors...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Sarabia, Indra, Novis, Camille L., Macedo, Amanda B., Takata, Hiroshi, Nell, Racheal, Kakazu, Juyeon C., Furler, Robert L., Shakya, Binita, Schubert, Heidi L., Hill, Christopher P., DePaula-Silva, Ana Beatriz, Spivak, Adam M., Trautmann, Lydie, Planelles, Vicente, Bosque, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8236643/
https://ncbi.nlm.nih.gov/pubmed/34194436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.682182
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