Activation of the Anti-Oxidative Stress Response Reactivates Latent HIV-1 Through the Mitochondrial Antiviral Signaling Protein Isoform MiniMAVS

The mitochondrial antiviral signaling protein (MAVS) is part of the cell’s innate immune mechanism of defense. MAVS mRNA is bicistronic and can give rise to a full length-MAVS and a shorter isoform termed miniMAVS. In response to viral infections, viral RNA can be sensed by the cytosolic RNA sensors...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Sarabia, Indra, Novis, Camille L., Macedo, Amanda B., Takata, Hiroshi, Nell, Racheal, Kakazu, Juyeon C., Furler, Robert L., Shakya, Binita, Schubert, Heidi L., Hill, Christopher P., DePaula-Silva, Ana Beatriz, Spivak, Adam M., Trautmann, Lydie, Planelles, Vicente, Bosque, Alberto
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8236643/
https://ncbi.nlm.nih.gov/pubmed/34194436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.682182
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