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NEMO, a transcriptional target of estrogen and progesterone, is linked to tumor suppressor PML in breast cancer

The beneficial versus detrimental roles of estrogen plus progesterone (E+P) in breast cancer remains controversial. Here we report a beneficial mechanism of E+P treatment in breast cancer cells driven by transcriptional upregulation of the NFκB modulator NEMO, which in turn promotes expression of th...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Valdez, Kelli E., Elsarraj, Hanan S., Hong, Yan, Grimm, Sandra L., Ricci, Lawrence R., Fan, Fang, Tawfik, Ossama, May, Lisa, Cusick, Therese, Inciardi, Marc, Redick, Mark, Gatewood, Jason, Winblad, Onalisa, Hilsenbeck, Susan, Edwards, Dean P., Hagan, Christy, Godwin, Andrew K., Fabian, Carol, Behbod, Fariba
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8236416/
https://ncbi.nlm.nih.gov/pubmed/28515148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2794
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