NEMO, a transcriptional target of estrogen and progesterone, is linked to tumor suppressor PML in breast cancer

The beneficial versus detrimental roles of estrogen plus progesterone (E+P) in breast cancer remains controversial. Here we report a beneficial mechanism of E+P treatment in breast cancer cells driven by transcriptional upregulation of the NFκB modulator NEMO, which in turn promotes expression of th...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Valdez, Kelli E., Elsarraj, Hanan S., Hong, Yan, Grimm, Sandra L., Ricci, Lawrence R., Fan, Fang, Tawfik, Ossama, May, Lisa, Cusick, Therese, Inciardi, Marc, Redick, Mark, Gatewood, Jason, Winblad, Onalisa, Hilsenbeck, Susan, Edwards, Dean P., Hagan, Christy, Godwin, Andrew K., Fabian, Carol, Behbod, Fariba
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8236416/
https://ncbi.nlm.nih.gov/pubmed/28515148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2794
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