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Extensive weight loss reduces glycan age by altering IgG N-glycosylation

BACKGROUND: Obesity, a major global health problem, is associated with increased cardiometabolic morbidity and mortality. Protein glycosylation is a frequent posttranslational modification, highly responsive to inflammation and ageing. The prospect of biological age reduction, by changing glycosylat...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Obes (Lond)
Prif Awduron: Greto, Valentina L., Cvetko, Ana, Štambuk, Tamara, Dempster, Niall J., Kifer, Domagoj, Deriš, Helena, Cindrić, Ana, Vučković, Frano, Falchi, Mario, Gillies, Richard S., Tomlinson, Jeremy W., Gornik, Olga, Sgromo, Bruno, Spector, Tim D., Menni, Cristina, Geremia, Alessandra, Arancibia-Cárcamo, Carolina V., Lauc, Gordan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8236401/
https://ncbi.nlm.nih.gov/pubmed/33941843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-021-00816-3
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