Extensive weight loss reduces glycan age by altering IgG N-glycosylation

BACKGROUND: Obesity, a major global health problem, is associated with increased cardiometabolic morbidity and mortality. Protein glycosylation is a frequent posttranslational modification, highly responsive to inflammation and ageing. The prospect of biological age reduction, by changing glycosylat...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Obes (Lond)
Auteurs principaux: Greto, Valentina L., Cvetko, Ana, Štambuk, Tamara, Dempster, Niall J., Kifer, Domagoj, Deriš, Helena, Cindrić, Ana, Vučković, Frano, Falchi, Mario, Gillies, Richard S., Tomlinson, Jeremy W., Gornik, Olga, Sgromo, Bruno, Spector, Tim D., Menni, Cristina, Geremia, Alessandra, Arancibia-Cárcamo, Carolina V., Lauc, Gordan
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8236401/
https://ncbi.nlm.nih.gov/pubmed/33941843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-021-00816-3
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