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Distinct Responsiveness of Tumor-Associated Macrophages to Immunotherapy of Tumors with Different Mechanisms of Major Histocompatibility Complex Class I Downregulation

SIMPLE SUMMARY: Tumor-associated macrophages (TAMs) are one of the major cell subpopulations in the tumor microenvironment (TME) where they can either be pro-tumorigenic or contribute to an anti-tumor immunity. The TME and TAM phenotype were analyzed after combined immuno-therapy (IT) in tumor model...

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Publicat a:Cancers (Basel)
Autors principals: Piatakova, Adrianna, Polakova, Ingrid, Smahelova, Jana, Johari, Shweta Dilip, Nunvar, Jaroslav, Smahel, Michal
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235485/
https://ncbi.nlm.nih.gov/pubmed/34205330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13123057
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