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CD80 Expression on Tumor Cells Alters Tumor Microenvironment and Efficacy of Cancer Immunotherapy by CTLA-4 Blockade

SIMPLE SUMMARY: The recent discovery of immune checkpoint inhibitors constituted a breakthrough in cancer treatment, but most patients are resistant to this therapy. Although the co-stimulatory molecule cluster of differentiation (CD) 80 has been detected in several types of tumor cells, its role in...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Vackova, Julie, Polakova, Ingrid, Johari, Shweta Dilip, Smahel, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072777/
https://ncbi.nlm.nih.gov/pubmed/33923750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13081935
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