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Abrogation of IFN-γ Signaling May not Worsen Sensitivity to PD-1/PD-L1 Blockade

Programmed cell death protein 1 (PD-1)/PD-1 ligand 1 (PD-L1) blockade is a promising therapy for various cancer types, but most patients are still resistant. Therefore, a larger number of predictive biomarkers is necessary. In this study, we assessed whether a loss-of-function mutation of the interf...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Vackova, Julie, Piatakova, Adrianna, Polakova, Ingrid, Smahel, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084912/
https://ncbi.nlm.nih.gov/pubmed/32155707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051806
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