Monocytes Expose Factor XIII-A and Stabilize Thrombi against Fibrinolytic Degradation

Factor XIII (FXIII) is a transglutaminase that promotes thrombus stability by cross-linking fibrin. The cellular form, a homodimer of the A subunits, denoted FXIII-A, lacks a classical signal peptide for its release; however, we have shown that it is exposed on activated platelets. Here we addressed...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Alshehri, Fahad S. M., Whyte, Claire S., Tuncay, Ahmet, Williams, Maria-Louise, Wilson, Heather M., Mutch, Nicola J.
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234680/
https://ncbi.nlm.nih.gov/pubmed/34205443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126591
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