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Role of Shear Stress and tPA Concentration in the Fibrinolytic Potential of Thrombi

The resolution of arterial thrombi is critically dependent on the endogenous fibrinolytic system. Using well-established and complementary whole blood models, we investigated the endogenous fibrinolytic potential of the tissue-type plasminogen activator (tPA) and the intra-thrombus distribution of f...

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Publicat a:Int J Mol Sci
Autors principals: Whyte, Claire S., Mostefai, Hadj Ahmed., Baeten, Kim M., Lucking, Andrew J., Newby, David E., Booth, Nuala A., Mutch, Nicola J.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924342/
https://ncbi.nlm.nih.gov/pubmed/33672724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22042115
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