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The Anti-Tumor Activity of the NEDD8 Inhibitor Pevonedistat in Neuroblastoma
Pevonedistat is a neddylation inhibitor that blocks proteasomal degradation of cullin–RING ligase (CRL) proteins involved in the degradation of short-lived regulatory proteins, including those involved with cell-cycle regulation. We determined the sensitivity and mechanism of action of pevonedistat...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8234433/ https://ncbi.nlm.nih.gov/pubmed/34207315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126565 |
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